New perspectives in lung cancer.5. New drugs in lung cancer.

New perspectives in lung cancer.5. New drugs in lung cancer.

Glucocorticoid receptors in lung cancer: new perspectives.

Proper expression of the glucocorticoid receptor (GR) plays an essential role in the development of the lung. GR expression and signalling in the lung is manipulated by administration of synthetic glucocorticoids (Gcs) for the treatment of neonatal, childhood and adult lung diseases. In lung cancers, Gcs are also commonly used as co-treatment during chemotherapy. This review summarises the effe...

New therapeutic perspectives in CCDC6 deficient lung cancer cells.

Non-small cell lung cancer (NSCLC) is the main cause of cancer-related death worldwide and new therapeutic strategies are urgently needed. In this study, we have characterized a panel of NSC lung cancer cell lines for the expression of coiled-coil-domain containing 6 (CCDC6), a tumor suppressor gene involved in apoptosis and DNA damage response. We show that low CCDC6 protein levels are associa...

New perspectives in lung cancer. 3. The antigens of lung cancer.

The growth of interest in the biology of lung cancer is a welcome product of frustration with the results of current treatment. The last 15 years have seen a considerable increase in our knowledge of the disease, and we can but hope that therapeutic advances will result. It is the most common cause of death from cancer in men, and in the United States in the last two years it has overtaken brea...

Ultrasonography in lung pathologies: new perspectives

BACKGROUND Nowadays, ultrasound techniques have not gained importance in the diagnosis and monitoring of lung pathologies yet because of the high mismatch in acoustic impedance between air and intercostal tissues. However, it is evident that B-mode imaging provides important information on pulmonary tissue, although in the form of image artifacts. FINDINGS Notwithstanding medical evidences, t...